sexual transmission of hepatitis c virus between hiv infected subjects and their main heterosexual partners

نویسندگان

abbas alipour community medicine department, school of medicine, mazandaran university of medical sciences, sari, ir iran; thalassemic research center, community medicine department, school of medicine, mazandaran university of medical sciences, sari, ir iran. tel: +98-15135430813, fax: +98-1513543248

abbas rezaianzadeh epidemiology department, school of health and nutrition, research center for health sciences, shiraz university of medical sciences, shiraz, ir iran

jafar hasanzadeh epidemiology department, school of health and nutrition, research center for health sciences, shiraz university of medical sciences, shiraz, ir iran

abdorreza rajaeefard epidemiology department, school of health and nutrition, research center for health sciences, shiraz university of medical sciences, shiraz, ir iran

چکیده

conclusions health care providers need to pay special attention to sexual transmission of hcv among hiv-infected individuals, and should recommend control/preventive measures for hcv sexual transmission. results age of the index samples was 38.71 ± 7 years, and 33.2 ± 6.3 for their main heterosexual partners; the mean duration of sexual relationship for couples was 11.9 (median = 8.5) years. multivariate analysis showed that actor risk factor of intravenous drug using (idu) (aor= 13.03; 95% ci: 3.9- 43.82) and actor cofactors of hiv positivity (aor = 7.1; 95% ci: 1.37- 36.97), razor sharing (aor = 4.81; 95% ci: 1.84- 12.55), sex (aor = 8.83; 95% ci: 3.16- 24.87), and condom use in sexual activity with main partner (aor = 0.15; 95% ci: 0.02- 0.44) were associated with actor hcv positivity. objectives the present study aimed to identify and quantitatively investigate hiv-infected individuals and their main heterosexual partners regarding the risk factors of hcv transmission. patients and methods one hundred sixty eight of 984 couples were chosen through random generated numbers using a computer program from behavioral consultation center in shiraz, iran. we used actor partner independent model (apim) and multilevel analysis to assess multiple risk factors for hcv, while partitioning the source of risk at the individual and couple levels. background overall, 60-70% of the hepatitis c virus (hcv) transmission routes is parenteral, and in 30-40% of the cases is unknown (e.g. sexual route). knowing these routes in hiv infected dyads is very important due to clinical and methodological reasons.

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عنوان ژورنال:
hepatitis monthly

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